Voldemort could be a main villain. Imagine him getting his hands on some of the Justice League's technology and using it to enhance his dark magic. He could become even more powerful and pose a threat not just to the wizarding world but also to the world the Justice League protects.
Darkseid could also be a main villain. He might see Harry's magic as a new source of power to conquer. He could invade the wizarding world, forcing Harry Potter and the Justice League to join forces to stop him. Darkseid's vast army and his own god - like powers would make for an epic battle against the combined forces of magic and superhero might.
Lex Luthor might be a great villain in this scenario. He could be intrigued by Harry's magic and try to find a way to use it for his own evil purposes. He might team up with some dark wizards from Harry's world and create a new kind of threat that combines magic and technology. Luthor's intelligence and cunning would make him a formidable foe against both Harry and the Justice League.
Darkseid as a vampire - like being. He could come to Earth and start turning people into his vampire minions. His already formidable powers combined with vampiric abilities would make him a terrifying foe for the Justice League.
Brainiac would be a great choice. He has advanced technology that could be a huge challenge for the OC gamer. The OC might have to use their gaming knowledge to outwit Brainiac's complex systems and plans. For instance, if Brainiac tries to assimilate the world's knowledge, the OC could use their strategic gaming skills to disrupt his data - collecting devices.
Darkseid would be a great main villain. He's already a powerful and well - known foe in the DC universe. He could be the one who starts collecting the Infinity Stones - like items to gain ultimate power and rule over all universes. His army could also be involved, making it a large - scale war for the Justice League.
It could be Eggman. He might team up with some of the Justice League's villains, like Lex Luthor. Eggman could bring his mechanical creations and knowledge of chaos emeralds, while Luthor provides his strategic mind and resources. Together, they could pose a huge threat to both Sonic and the Justice League.
The Highbreed could also serve as the main villain. They are a powerful and xenophobic race in the Ben 10 universe. In a crossover, they might view the Justice League's world as a place to expand their territory. They could use their advanced technology and large numbers to attack. Ben would have to convince the Justice League that the Highbreed are a serious threat and together they would need to find a way to stop the Highbreed's invasion, perhaps by using Ben's alien forms like Upgrade to hack into their technology and the Justice League's strategic planning.
It could be a combined force of Voldemort and one of the major Justice League villains like Darkseid. Voldemort might be attracted to Darkseid's power and they form an alliance. Their goal could be to take over both the wizarding world and the world where the Justice League exists. They would use their combined magic and super - villain powers to create chaos and destruction.
Well, I think Batman and Hermione could be main characters. Batman's intelligence and detective skills combined with Hermione's vast knowledge of magic would make for an interesting dynamic. They could be the ones leading the team in strategizing against the common enemies that the crossover would bring. Also, Wonder Woman and Ginny Weasley could be important. Wonder Woman's strength and combat skills paired with Ginny's talent in magic, especially her Bat - Bogey Hex, could make them a formidable duo in the story.
It could be a wild adventure where Harry Potter, with his magical abilities, teams up with the Justice League. Maybe Harry uses his spells to enhance the League's powers or to combat enemies that are immune to their usual tactics. For example, he could use a Patronus charm to fend off some dark, mind - controlling villains that the League has trouble with.
A good main villain could be Brother Eye. It's a powerful and menacing artificial intelligence. In a crossover, it could have evolved in the future to be even more dangerous. It could pose a threat to both the future world of Batman Beyond and the past era of the Justice League, forcing them to team up to take it down.
Most likely Naruto himself would be one of the main characters. And perhaps some of the well - known Justice League members like Batman or Wonder Woman could also be main characters.