Perhaps he realizes that magic has corrupted the wizarding world in some ways. There could be political unrest or dark magic influencing too many things. In the fanfiction, he gives up his magic to make a statement or to try and change the wizarding world from the outside.
Maybe he was tired of the constant danger and responsibility that came with magic. In the original series, he faced so many threats. In fanfiction, he might just want a normal life away from all that.
In some fanfiction scenarios, he might give up magic for love. For example, if he falls in love with a Muggle who is afraid of magic or if he wants to live a normal life with his non - magical loved ones. He may think that by giving up magic, he can have a more stable and ordinary relationship.
One possible reason could be that he has seen too much destruction and chaos caused by magic. He might feel that it brings more harm than good, so he decides to give it up.
One possible reason could be the overwhelming burden of his destiny. Constantly facing dark forces and the pressure of saving the wizarding world might have worn him down. Another reason could be the loss of his loved ones. For example, if in the fanfiction Hermione or Ron were killed, that could shatter his spirit.
In some fanfiction, Harry might renounce his name to explore a new identity. He has been through so much as Harry Potter, and by giving up his name, he can break free from the predefined roles and destinies associated with it. He could then embark on a journey of self - discovery, free from the constraints of the name that has both defined and haunted him.
One possible reason could be that in the fanfiction, Harry might have discovered some dark secrets about his parents that made him feel betrayed. For example, if he found out they had some hidden and unethical magical experiments in their past.
In some fanfictions, his family might be involved in dark magic or have a bad reputation. So, Harry Potter refuses them to uphold his own moral values. He is known for his strong sense of right and wrong, and if his family goes against that, he would distance himself.
One possible reason could be that he might feel abandoned. Growing up without them, he could resent the fact that they left him an orphan. He might think that if they were really so great, they would have found a way to survive and be there for him.
Perhaps he discovers some secrets about his parents that he doesn't like. For example, he might find out that they were involved in some dangerous or unethical magic before. This new knowledge could make him angry at them for putting themselves and their family in jeopardy.
One reason could be to gain power. In fanfiction, the author might want to show Harry in a situation where he needs a significant boost in power and blood magic seems like a way to achieve that. Another reason could be for revenge. If he's been wronged greatly, he might turn to blood magic as a more extreme form of retaliation.
Maybe he was hit by a powerful dark magic spell specifically designed to target the soul. Such spells in the Harry Potter universe can be extremely dangerous.