Draco Malfoy could be another main character. He might be initially glad that Snape has lost his memory as he no longer has to fear Snape's strictness or authority. But as the story progresses, he could come to realize the importance of Snape in the wizarding world and even try to help him regain his memories, perhaps out of a new - found sense of loyalty or just because he realizes the chaos that Snape's permanent memory loss could cause.
Luna Lovegood could be a character in such fanfiction. Given her unique perspective on things, she might have an interesting take on Snape's memory loss. She could offer some unorthodox solutions or just be a calming presence in the chaos that follows Snape's changed state. And of course, Dumbledore might be involved as he has always had a complex relationship with Snape and would surely be interested in how this memory loss affects Snape and the future of Hogwarts.
Well, Severus Snape is obviously the central character. But often, other characters from the Harry Potter series are also involved. Harry Potter himself is frequently present as his relationship with Snape is a key part of the original story. Hermione Granger and Ron Weasley may also show up, as they are important in the wizarding world and their interactions with Snape can be explored in different ways in fanfiction.
Obviously, Harry Potter himself is the central character. Since the story is about him losing his sanity, he is at the core of the plot. Then there would likely be his friends like Hermione and Ron. Their reactions to Harry's deteriorating mental state would be important aspects of the story. They might try to help him, or they could be at a loss about what to do.
Obviously Naruto himself is the central character since the story is about him losing his memories. Sakura would likely be involved too. She's one of Naruto's closest friends and a medic - ninja, so she might try to find a way to restore his memories.
One plotline could be Snape forgetting his past enmities, especially towards Harry Potter. This might lead to an unexpected friendship developing between them as Snape no longer holds the grudges from before. He could start seeing Harry in a new light and they might work together to uncover secrets about the wizarding world that were previously clouded by their animosity.
There could be a girl named Bella who might be his love interest. She could be the one trying to help Edward regain his memory. Another character could be his best friend, Jacob, who is always by his side, protecting him while he's in this vulnerable state.
It could be Orochimaru. He's always been interested in Naruto's power. Maybe he devises a plan to make Naruto lose his memory so he can manipulate him more easily, perhaps to use him as a weapon against the Hidden Leaf.
It could be a new villain who has the power to manipulate memories. This villain might target Deku specifically because he sees Deku as a threat to his plans. He wants to erase Deku's memory so that he can't interfere with his evil schemes in the hero world.
It could be a marine admiral who has developed a new weapon that not only causes physical harm but also memory loss. This admiral might see Luffy as a big threat and decides to use this weapon on him to weaken the Straw Hat crew.
In a lot of these fanfictions, Luna Lovegood can be a key character. She has an open - minded and unique way of looking at things. So she might be the one who first suspects that Harry isn't really dead, or she could be part of the plan to help Harry fake his death and then communicate with him in some secret way while everyone else thinks he's gone.
The main character is Merlin, of course. He is the focus as he is the one with the hidden pain. Arthur Pendragon is a key figure too. Since Merlin is Arthur's manservant, Arthur's actions, words, or even his ignorance of Merlin's true self can be sources of Merlin's pain. Sometimes, the Great Dragon can also be involved. The dragon might be aware of Merlin's pain and offer some cryptic advice that Merlin has to decipher while still hiding his pain from others.