It could be a rogue ninja from a neighboring village who has a vendetta against Konoha. This ninja might see Naruto's return as an opportunity to take on the strongest ninja in Konoha and prove his own strength.
Perhaps it's an old enemy who has somehow managed to come back stronger. Maybe someone from Orochimaru's old experiments that went wrong, but instead of dying, they gained some dark and powerful abilities. They see Naruto's return as a threat to their plans of world domination, so they target Konoha first. They might be able to control dark chakra in a way that no one has seen before, and use it to create chaos and destruction. They could also have some minions who are equally as powerful and loyal to them, making them a formidable foe for Naruto and Konoha.
The Konoha elders could be the main antagonists. They are often shown to be quite traditional and set in their ways in the original series. If Naruto goes against their old - fashioned ideas about the village's future and ninja code, they would likely oppose him strongly and could be the driving force behind making Naruto an outcast, which in turn could lead to his 'betrayal'.
It could be Orochimaru. He has always had his eyes on Konoha and might find a way to manipulate Naruto into attacking it. Maybe he uses some new experimental jutsu on Naruto to make him do his bidding.
It could be a new villain who has been plotting against Konoha while Naruto was away.
It could be a rogue ninja from another village who has a vendetta against Naruto. This ninja might spread false rumors about Naruto in Konoha, which eventually leads to Naruto leaving. So, this ninja would be the main antagonist as he is the root cause of Naruto's departure.
It could be some of the more conservative village elders in Konoha. They might see Naruto Namikaze's unorthodox ways and growing power as a threat to their traditional way of running the village. So they create situations that make Naruto feel unwelcome and eventually lead to his departure, making them the antagonists in the story.
It could be a rogue ninja from within Konoha who doesn't want Naruto to return because he fears Naruto's growing power will disrupt his own plans for power within the village.
A new character could be the main antagonist. This character could be from a far - off land that Naruto has never encountered before. This antagonist has heard of Naruto's power and wants to prove himself by defeating Naruto and taking over the Hidden Leaf. He might have unique powers and a large army at his disposal. He could also be manipulating some of the villagers from the inside to create chaos before making his big move.
It could be Orochimaru. He's always been interested in Konoha's secrets and might have found a way to use Naruto's clones for his own purposes. He could be manipulating the clones from the shadows to steal forbidden jutsu scrolls or something similar.
Perhaps Danzo could be the main antagonist. He was always a bit of a shadowy figure in the original Naruto series. In this fanfic, he might see Naruto and Sasuke as a threat to his own control over Konoha. So, he uses his influence to have them banished. He could be secretly working with external forces to further his own agenda while keeping Naruto and Sasuke away from Konoha.