One idea could be that Greed finds himself in an alternate universe where the rules of alchemy are slightly different. He could then try to adapt and use this new knowledge to his advantage, all while facing new and unexpected enemies. Another plot could involve Greed teaming up with characters from another fandom in a quest for a powerful and mysterious object that exists in both worlds.
One plot idea could be that Ichigo somehow gets transported to the FMA world. He might initially be confused by the alchemical rules but then use his Soul Reaper powers in unique ways. For example, his Zanpakuto could be seen as a form of alchemical weapon, and he could fight alongside the Elric brothers against the homunculi. Another idea is that the Philosopher's Stone has some connection to the Hollow within Ichigo, and characters from both universes have to work together to prevent a catastrophic event.
Well, a cool plot could be that the Death Eaters are interested in the power of alchemy. They try to capture Edward to force him to use alchemy for their evil purposes. Harry, Ron, and Hermione then rescue him. In return, Edward offers to help them with his alchemical skills in their fight against Voldemort. For example, he could use alchemy to create unique magical items or barriers. Also, Alphonse could befriend some of the Hogwarts ghosts and learn about the secrets of the castle from them, which could be useful in the fight against the dark side.
One idea could be that Naruto characters are somehow transported to the FMA world and have to adapt to the rules of alchemy. For example, Naruto might be intrigued by the concept of equivalent exchange and try to apply his ninja way to it. He could learn alchemy and use his chakra in unique ways to manipulate it.
First, know the characters well. Understand Greed's personality, his desires, and his powers in FMA. Then, research the other fandom you want to crossover with. Next, create a unique and engaging plot that combines elements from both worlds in a seamless way. For example, if it's a crossover with a fantasy world, think about how Greed's alchemical nature would interact with magic. Don't forget to develop good character relationships and let the story flow naturally.
One plot idea could be Envy being forced to confront his own envy in a very personal way. Maybe he sees someone with a life he secretly desires and it makes him question his own actions. Another could be a story where Envy has a change of heart due to an unexpected encounter, like meeting a kind-hearted human who doesn't immediately judge him.
The contrast between their characters. Greed is a homunculus with his own desires and motives, while Winry is a kind - hearted and determined mechanic. Their interactions can be full of tension and unexpected moments.
A really interesting fma crossover fanfic idea might be with the world of Fullmetal Alchemist and the Lord of the Rings. Imagine the Elric brothers in Middle - earth, facing the challenges there. They could use their alchemy skills in a world filled with magic, elves, and orcs. It would be a very unique combination as the concepts of alchemy and the magic in Middle - earth are quite different.
Maybe a story where the OC is a powerful being that Greed tries to manipulate into working for him. The OC, being smart, plays along at first but then turns the tables on Greed, teaching him a lesson about true power not being just about possessions.
One idea could be that characters from Fma use their alchemical skills in the wizarding world of Harry Potter. For example, Edward could try to transmute a magical object using his knowledge of equivalent exchange. Another plot idea might be that the Philosophers Stone from Harry Potter has some connection to the alchemy in Fma, and characters from both universes have to work together to protect it from dark forces. Also, perhaps a character from Fma gets sorted into one of the Hogwarts houses and has to adapt to the magical school life while still having their own alchemical powers.
Often, there's the theme of redemption. Greed is not a completely 'good' character in the original FMA. In fanfiction, his relationship with the reader can be a catalyst for him to seek redemption or change. There's also the theme of adventure. The FMA world is full of danger and mystery, and the reader and Greed might embark on adventures together, facing various challenges along the way. This can range from fighting other alchemists to dealing with the secrets of the Philosopher's Stone.