Obviously, Voldemort as a baby would be one of the main characters. Harry Potter could also be a main character as he has a long - standing enmity with Voldemort. He might be involved in deciding the fate of the baby - voldemort. Dumbledore would surely play a major role. His wisdom would be needed to deal with this strange situation. And Hermione, with her vast knowledge of magic, could be involved in trying to find a way to either reverse the transformation or ensure that the baby Voldemort grows up to be good.
The main characters could be baby Voldemort himself, of course. Then, there could be a new character, a young and inexperienced wizard who stumbles upon the baby. This wizard doesn't recognize Voldemort at first and decides to take care of him. Ron Weasley could also be a main character. He might be skeptical about the whole idea of trying to reform baby Voldemort. His more down - to - earth view could add an interesting dynamic to the story. And Nagini, Voldemort's snake, could be in the story too. She might sense that the baby is her master and protect him in her own way.
One possible plot could be that the magic backfires on Voldemort during a powerful dark spell. As a baby, he has no memory of his previous self. The wizarding world is in chaos as they don't know what to do with this baby - voldemort. Some might want to kill him immediately, while others think he could be redeemed. Harry Potter, having defeated him once, feels a strange sense of responsibility and wants to make sure he doesn't grow up to be evil again.
Obviously, Sonic himself would be a main character, even in his baby form. His friends like Tails, Knuckles, and Amy would also be main characters. Tails could be the one trying to figure out how to turn Sonic back. Knuckles could be the protector, and Amy could be the caretaker.
Obviously, Ash would be a main character even in his baby form. Pikachu is bound to be a key character as well, being Ash's closest Pokémon partner. His other Pokémon like Bulbasaur, Charmander, and Squirtle could also play important roles in protecting and taking care of baby Ash.
Obviously, Shadow himself would be a main character even in his baby form. Sonic would also be a key character as he is often the hero in these Sonic - related stories. He would likely be involved in trying to figure out how to turn Shadow back. Tails could be another main character as his intelligence would be useful in finding a solution to Shadow's transformation. He might study the cause of it and try to come up with a remedy.
Mario would definitely be a main character. Since Luigi is his brother, he would be the one most concerned about Luigi's transformation and would do everything he could to help him. Princess Peach could also be a main character. She might offer her castle as a safe place for baby Luigi and use her resources to find a solution. Toad could be there too, helping Mario with taking care of Luigi and providing useful information about the kingdom that could lead to reversing the spell.
Perhaps a mysterious stranger. This stranger could have some connection to the reason why Edward turned into a baby. And then there's Edward's pet dog. The dog might be confused at first but then becomes very protective of baby Edward, adding an interesting dynamic to the story.
Her best friend could be a main character. They might be the one who is most affected by her transformation and has to take on a lot of responsibility in taking care of her.
Erza could also be a main character. Given her strong and motherly side, she would probably take on the role of taking good care of baby Lucy. She might be strict about following a routine for baby Lucy's care. Happy, the flying cat, could be another important character. He could use his unique abilities to search for clues on how to turn Lucy back to normal.
His guildmates would surely be main characters. For example, Natsu could be there. Natsu might be really confused at first but then would be super protective of baby Laxus. Another could be Lucy. She might be the one who is more practical in taking care of the baby, like making sure he has proper clothes and a comfortable place to sleep.
Rukia could be the main caregiver. She has a close bond with Ichigo and has always been there for him. She would probably be the most likely to take on the role of looking after him, making sure he's fed, clean, and safe.