One idea could be a crossover with Star Trek. Darth Vader could find himself on the Enterprise and have to deal with the Federation's values, which are very different from the Sith's. Maybe he'd be forced to team up with Kirk and Spock to fight a common enemy.
A crossover with the Lord of the Rings universe. Darth Vader could enter Middle - earth. He'd probably be intrigued by the power of the One Ring. He might see Sauron as a kind of rival in terms of domination. And he could interact with characters like Aragorn or Gandalf, creating some really interesting storylines.
A cool concept would be a crossover with the Star Trek universe. Darth Vader's Sith ideology would clash with the Federation's principles. He might be intrigued by the advanced technology of the Star Trek world, and there could be an epic battle between the power of the Force and the technology of the future. Or perhaps he'd form an unlikely alliance with some of the more morally ambiguous characters in Star Trek.
One idea could be exploring Darth Vader's identity before he became encased in the suit. Maybe he rediscovers his old self and tries to reconnect with his past relationships. Another could be him having to face the Jedi without the intimidating suit, relying solely on his raw Force abilities.
One idea could be a crossover where Darth Vader somehow ends up in the wizarding world. Maybe he's mistaken for a very powerful dark wizard and Hogwarts has to figure out how to deal with him. Another could be a story where Harry Potter discovers the Force and has to learn to use it alongside his magic. A third idea might be a scenario where Darth Vader is resurrected in the Potterverse and teams up with Voldemort, causing chaos for the Order of the Phoenix.
Perhaps Darth Vader's dark side powers are misinterpreted in the Naruto world as a new and extremely dangerous form of jutsu. Naruto and his friends might try to find a way to seal these powers. Meanwhile, Vader is on a quest to find a way back to his own universe, and in the process, he starts to question his own dark ways after seeing the camaraderie among the Naruto characters. He could end up having a change of heart and use his powers for good in the Naruto universe.
One idea could be a story where Darth Vader discovers Leia's true identity earlier and struggles with his loyalty to the Empire and his newfound knowledge of his daughter. He could secretly protect her from the Emperor's wrath.
One idea could be a fanfic where Darth Vader has a secret apprentice who is an original character. This OC could be a young Force - sensitive being from a hidden planet. The story could revolve around Vader training this apprentice in the ways of the Dark Side, while also facing internal conflict as he sees some of his own past self in this young OC.
Another plot could be set in an alternate universe where Ahsoka manages to reach out to the little bit of Anakin still left in Darth Vader. She tries to redeem him, and through a series of encounters, they start to question their own paths and the Sith vs. Jedi ideology.
One idea could be that the OC is a rebel spy who gets captured by Darth Vader. Instead of killing her immediately, he becomes intrigued by her tenacity and they start to have a series of tense conversations that gradually lead to an unexpected understanding between them.
One idea could be a story where Darth Vader secretly trains Luke in the ways of the Force before Luke fully realizes who he is. This would add an interesting layer of secrecy and moral conflict for Vader.
One idea could be a story where Luke discovers a way to temporarily reverse Vader's Sith corruption, leading to some heart - to - heart conversations between them as Anakin. Another could be a fanfic where they have to team up against a new, greater threat in the galaxy that neither the Rebels nor the Empire can handle alone. Maybe a story where Luke gets trapped in a Sith - created alternate dimension and Vader has to go in and rescue him to atone for his sins.