Does Goku go Ultra Instinct in the manga?

Yes, he does. Goku achieves Ultra Instinct in the manga.

Goku definitely masters Ultra Instinct in the manga. This transformation gives him a huge boost in power and allows him to take on even stronger opponents.

Yes, he does. Vegeta achieves Ultra Instinct in the manga at a crucial point in the story.

Yes, he did. Goku achieves mastery of Ultra Instinct in the manga after intense training and battles.

Yes, Goku has mastered Ultra Instinct in the manga.

Yes, eventually. As the story progresses, Goku gains more control and can use Ultra Instinct more freely.

Not as far as I know. Ultra Instinct Goku is pretty much a force to be reckoned with and hasn't been beaten in the manga.

Not that I know of. Ultra Instinct Goku is a pretty powerful form and it's rare for anyone to outright defeat him in the manga.

In the manga, Ultra Instinct is not achieved by Vegeta. The power-up is mainly associated with Goku's development and storyline.

Yes, it is possible. In fanfiction, writers have the creative freedom to reimagine the origin of characters. Goku being born with Ultra Instinct can add a whole new layer to his character development. It could mean that his power growth would be different from the original story, perhaps faster or with different challenges along the way.