First off, you have to have a passion for comics. Then, come up with a compelling idea that stands out. Partner with talented illustrators and writers. Establish an online presence and collaborate with other comic creators for cross-promotion.
To make a comic book business thrive, start with a unique and engaging story. Then, invest in quality illustrations and a professional layout. Build a brand around it and promote through social media and comic conventions.
You need a great concept and good artists. Also, marketing and finding the right audience are crucial.