Sure, you can. English is a widely used language and there's no rule against creating manga in it.
Yes, you definitely can. Many successful mangas have been created in English. It gives you the opportunity to reach a wider audience. Just make sure your story and art are engaging and well-presented.
Of course! Creating a manga in English is possible. You'll have the advantage of communicating with a large number of English speakers. But keep in mind that you need to have a good understanding of the language and the cultural nuances to make it appealing to the readers.