One way is to think about a theme or message you want to convey and build a plot around that. Another approach is to start with a fascinating character and imagine the adventures they could have. And don't be afraid to throw in some mystery or suspense to keep readers hooked.
Well, you could draw inspiration from real-life events, combine different genres, or play around with classic story structures and give them a modern twist. Also, observing people and their behaviors can spark some great plot ideas.