Does One Punch Man ever lose in the manga?

Yes, there is. One Punch Man has a popular manga series.

Saitama doesn't lose in the manga. He's basically unbeatable with his insane strength.

Genos is still kicking in the One Punch Man manga. The author has managed to keep him in the storyline without killing him off. There's always the possibility in the future, but for now, he's alive and fighting.

Overall, One Punch Man follows the manga quite closely. There are some minor differences for better animation adaptation and pacing, but the core story and characters remain intact.

The ending of One Punch Man manga is quite unexpected. Saitama faces a powerful final enemy but resolves the situation with his trademark one-punch style, while also bringing some closure to character arcs.

Well, the end of One Punch Man in the manga comes after a series of intense battles and character developments. It ties up many loose ends but leaves some room for interpretation. I'd recommend reading it yourself to fully experience the conclusion.

Yes, it is. The story concluded after a certain number of volumes.

Yes, it's over. The story has reached its conclusion.

Sure is. The humor in it is spot-on, and the way it plays with superhero tropes is refreshing. The world-building is also top-notch.

Yes, it is. The manga concluded after a successful run.