The effect of disease on the works of van der Bowe can be seen in the following examples: When he was young, he suffered from a severe lung disease, which had a profound impact on his music career. In the later stages of his life, his physical condition deteriorated and he eventually died of illness. The death of Bach had a certain impact on his music. His illness prevented him from focusing on music for a long time and required constant rehabilitation and treatment. This also affected the time he spent composing, making his music career go through many difficult periods, including some famous works he created while he was deaf and mute. The state of his health also influenced the style and theme of his music. In the early years of his life, his songs usually expressed strong emotions and personal topics, but in his later years, his songs became more complex and abstract, exploring more musical forms and techniques. The disease had a profound impact on his works, his music composition and his life experience.